Chemical risks that nurses are exposed in antineoplastic therapy services in a hospital setting: a systematic review protocol


  • Trajano Felipe Barrabas Xavier da Silva Universidade do Porto
  • Humberto Costa Universidade Federal do Paraná
  • Marcelo Montebello Ribeiro Universidade do Porto



Occupational health, Occupational exposure, Occupational risk, chemotherapy drugs, antineoplastic drugs.


Chemotherapy is a complex and highly specialized process that involves risk, and the success of the results largely depends on the nursing care provided to the patient. Contamination with antineoplastic chemotherapy can occur directly through the skin, membranes, mucous membranes and inhalation or indirectly through body fluids and excreta from patients who received medication within 72 hours. The effects of contamination may be immediate (dermatitis, skin hyperpigmentation and others) or late (partial alopecia, chromosomal abnormalities and increased risk of developing cancer), with risks arising from the inherent toxicity of the drug and the exposure time of individuals. antineoplastic agents. Indispensable care is required for the nursing staff in the administration of chemotherapy, in addition to the institutions providing adequate safety measures for the work of these professionals. Thus, a systematic review is proposed to obtain relevant information on these risks to plan appropriate future interventions to avoid related negative consequences. Thus, following the preferred reporting items for systematic reviews and meta-analysis protocols (PRISMA-P), this systematic review protocol was designed to provide appropriate guidelines for the development of research that can provide results to meet the goal sought. Five databases will be accessed (SCOPUS, PubMed, Science Direct, EBSCOhost, and Web of Science) and a total of 9 keyword combinations will be used. This protocol is registered in PROSPERO under the code of PROSPERO CRD42019131696

Biografia do Autor

Trajano Felipe Barrabas Xavier da Silva, Universidade do Porto

Possui graduação em Farmácia pela Universidade Federal do Paraná (1991) e graduação em Design de Produto pela Universidade Tuiuti do Paraná (2002) . Possui especialização em Produtos Naturais pela Universidade Federal do Paraná (1987) e mestrado profissionalizante em Gestão Ambiental pela Universidade Positivo (2007). Atualmente é professor adjunto da Universidade Positivo e do Centro Universitário Uniandrade. Ministrou as disciplinas de Deontologia e Legislação Farmacêutica e Administração e Gestão Farmacêutica. Atualmente ministra as disciplinas de Farmacotécnica, Tecnologia de Cosméticos e Farmácia Hospitalar. Coordena o Estágio Supervisionado em Farmácia e Estágio Supervisionado em Indústria.



Como Citar

Silva, T. F. B. X. da, Costa, H., & Ribeiro, M. M. (2021). Chemical risks that nurses are exposed in antineoplastic therapy services in a hospital setting: a systematic review protocol. Scientific Electronic Archives, 14(3), 112–115.