Accuracy of the Brazilian version of the Prefrontal Symptoms Inventory (PSI-16) in the neuropsychological assessment of patients diagnosed with Alzheimer's disease

Autores

  • Olívia Dayse Leite Ferreira Centro Universitário Uniesp
  • João Pedro dos Santos Cipriano Centro Universitário Uniesp
  • João Carlos Alchieri Universidade Federal do Rio Grande do Norte

DOI:

https://doi.org/10.36560/151020221598

Palavras-chave:

neuropsychological tests, Alzheimer, Accuracy, Prefrontal cortex

Resumo

The aim of the present study was to ascertain the accuracy of the Prefrontal Symptoms Inventory (PSI-16) for patients with probable Alzheimer, as well as to compare it with the Mini Mental State Examination (MMSE) and the Frontal Assessment Battery (FAB). The study included 159 elderly people, aged over 60 years, 50 with a diagnosis of probable Alzheimer and 109 without the pathology. In the total sample, the cut-off point of the PSI-16 was > 19 points, with sensitivity and specificity moderate. Accuracy in the group with a ³ 8 years of education was superior in all instruments. The AUCs of PSI-16 and MMSE remained similar, the SE of all instruments increased, and the SP obtained a decline, considering the elderly over 70 years old. PSI-16 is a self-report instrument suitable for tracking behavioral problems related to the prefrontal cortex, with little impact from age and education level.

Referências

AMERICAN PSYCHIATRY ASSOCIATION. Diagnostic and Statistical Manual of Mental disorders - DSM-5. 5 ed. Washington: American Psychiatric Association, 2013. Disponível em: https://www.psychiatry.org/psychiatrists/practice/dsm.

BAUDIC, S. et al. L. Executive function deficits in early Alzheimer’s disease and their relations with episodic memory. Archives of Clinical Neuropsychology, v. 21, n. 1, p. 15–21, 2006. DOI: https://doi.org/10.1016/j.acn.2005.07.002.

BEATO, R. et al. Frontal assessment battery in a Brazilian sample of healthy controls: Normative data. Arquivos de Neuro-Psiquiatria, v. 70, n. 4, p. 278–280, 2012. DOI: https://doi.org/10.1590/S0004-282X2012005000009.

BRAUN, M. et al. Neuropsychological Assessment: A Valuable Tool in the Diagnosis and Management of Neurological, Neurodevelopmental, Medical, and Psychiatric Disorders. Cognitive and Behavioral Neurology, v. 24, n. 3, p. 107–114, 2011. DOI: https://doi.org/10.1097/WNN.0b013e3182351289.

BRUCKI, S. M. D. et al. Sugestões para o uso do mini-exame do estado mental no Brasil. Arquivos de Neuro-Psiquiatria, v. 61, n. 3B, p. 777–781, 2003. DOI: https://doi.org/10.1590/S0004-282X2003000500014.

CHONG, M. S. et al. Diagnostic Performance of the Chinese Frontal Assessment Battery in Early Cognitive Impairment in an Asian Population. Dementia and Geriatric Cognitive Disorders, v. 30, n. 6, p. 525–532, 2010. DOI: https://doi.org/10.1159/000321665.

CROUS-BOU, M.; MINGUILLÓN, C.; GRAMUNT, N.; MOLINUEVO, J. L. Alzheimer’s disease prevention: From risk factors to early intervention. Alzheimer’s Research & Therapy, v. 9, n. 1, p. 71, 2017. DOI: https://doi.org/10.1186/s13195-017-0297-z.

DE ARAUJO, N. B. et al. Diagnosing dementia in lower educated older persons: Validation of a Brazilian Portuguese version of the Rowland Universal Dementia Assessment Scale (RUDAS). Revista Brasileira de Psiquiatria, v. 40, n. 3, p. 264–269, 2018. DOI: https://doi.org/10.1590/1516-4446-2017-2284.

DONG, Y. et al. The Montreal Cognitive Assessment is superior to the Mini–Mental State Examination in detecting patients at higher risk of dementia. International Psychogeriatrics, v. 24, n. 11, p. 1749–1755, 2012. DOI: https://doi.org/10.1017/S1041610212001068.

DUBOIS, B.; SLACHEVSKY, A.; LITVAN, I.; PILLON, B. The FAB: A frontal assessment battery at bedside. Neurology, v. 55, n. 11, p. 1621–1626, 2000. DOI: https://doi.org/10.1212/WNL.55.11.1621.

FARFEL, J. M. et al. On behalf of the Brazilian Aging Brain Study Group. Very low levels of education and cognitive reserve: A clinicopathologic study. Neurology, v. 81, n. 7, p. 650–657, 2013. DOI: https://doi.org/10.1212/WNL.0b013e3182a08f1b.

FERREIRA, O. D. L.; BARBOSA, L. N. F.; ALCHIERI, J. C. Validity Evidences of the Prefrontal Symptoms Inventory for the Elderly Brazilian Population. Clinics, v. 75, e1863, 2020. DOI: https://doi.org/10.6061/clinics/2020/e1863.

FOLSTEIN, M. F.; FOLSTEIN, S. E.; MCHUGH, P. R. “Mini-mental state”. Journal of Psychiatric Research, v. 12, n. 3, p. 189–198, 1975. DOI: https://doi.org/10.1016/0022-3956(75)90026-6.

GERSTENECKER, A. et al. Exploring the Factor Structure of Financial Capacity in Cognitively Normal and Impaired Older Adults. Clinical Gerontologist, v. 41, n. 1, p. 33–41, 2018. DOI: https://doi.org/10.1080/07317115.2017.1387211.

JOE, E.; RINGMAN, J. M. Cognitive symptoms of Alzheimer’s disease: Clinical management and prevention. BMJ, v. 367, 2019. DOI: https://doi.org/10.1136/bmj.l6217.

LAKS, J. et al. O mini exame do estado mental em idosos de uma comunidade: Dados parciais de Santo Antônio de Pádua, RJ. Arquivos de Neuro-Psiquiatria, v. 61, n. 3B, p. 782–785, 2003. DOI: https://doi.org/10.1590/S0004-282X2003000500015.

LIU, Y. et al. Education increases reserve against Alzheimer’s disease—Evidence from structural MRI analysis. Neuroradiology, v. 54, n .9, p. 929–938, 2012. DOI: https://doi.org/10.1007/s00234-012-1005-0.

MACKIN, R. S.; AYALON, L.; FELICIANO, L.; AREÁN, P. A. The Sensitivity and Specificity of Cognitive Screening Instruments to Detect Cognitive Impairment in Older Adults With Severe Psychiatric Illness. Journal of Geriatric Psychiatry and Neurology, v. 23, n. 2, p. 94–99, 2010. DOI: https://doi.org/10.1177/0891988709358589.

MANTZAVINOS, V.; ALEXIOU, A. Biomarkers for Alzheimer’s Disease Diagnosis. Current Alzheimer Research, v. 14, n. 11, 2017. DOI: https://doi.org/10.2174/1567205014666170203125942.

MELO, D. M.; BARBOSA, A. J. G. O uso do Mini-Exame do Estado Mental em pesquisas com idosos no Brasil: Uma revisão sistemática. Ciência & Saúde Coletiva, v. 20, n. 12, 2015, 3865–3876. DOI: https://doi.org/10.1590/1413-812320152012.06032015.

NAKAAKI, S. et al. A. Reliability and validity of the Japanese version of the Frontal Assessment Battery in patients with the frontal variant of frontotemporal dementia. Psychiatry and Clinical Neurosciences, v. 61, n. 1, p. 78–83, 2007. DOI: https://doi.org/10.1111/j.1440-1819.2007.01614.x.

NITZSCHE, B. O.; MORAES, H. P.; TAVARES JÚNIOR, A. R. Alzheimer’s disease: New guidelines for diagnosis. Revista Médica de Minas Gerais, v. 25, n. 2, 2015. DOI: https://doi.org/10.5935/2238-3182.20150043.

NHO, K. et al. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Molecular Psychiatry, v. 18, n. 7, p. 781–787, 2013. DOI: https://doi.org/10.1038/mp.2013.24.

OGURO, H. et al. Differentiating Alzheimer’s disease from subcortical vascular dementia with the FAB test. Journal of Neurology, v 253, n. 11, p. 1490–1494, 2006. DOI: https://doi.org/10.1007/s00415-006-0251-7.

ORTEGA, L. F. V. et al. Screening for Alzheimer’s disease in low-educated or illiterate older adults in Brazil: A systematic review. Arquivos de Neuro-Psiquiatria, v. 77, n. 4, p. 279–288, 2019. DOI: https://doi.org/10.1590/0004-282x20190024.

PATEL, V.; PRINCE, M. Ageing and mental health in a developing country: Who cares? Qualitative studies from Goa, India. Psychological Medicine, v. 31, n. 1, p. 29–38, 2001. DOI: https://doi.org/10.1017/S0033291799003098.

PAULA, J. J. et al. Screening for Executive Dysfunction with the Frontal Assessment Battery: Psychometric Properties Analysis and Representative Normative Data for Brazilian Older Adults. Psicologia em Pesquisa, v. 7, n. 1, p. 89–98, 2013. DOI: https://doi.org/10.5327/Z1982-1247201300010010.

PEDRERO-PÉREZ, E. J. et al. Inventario de síntomas prefrontales (ISP): Validez ecológica y convergencia con medidas neuropsicológicas. Revista de Neurología, v. 63, n. 6, p. 241, 2016. DOI: https://doi.org/10.33588/rn.6306.2016143.

PEREIRA, F. S. et al. Profiles of functional deficits in mild cognitive impairment and dementia: Benefits from objective measurement. Journal of the International Neuropsychological Society, v. 16, n. 2, p. 297–305, 2010. DOI: https://doi.org/10.1017/S1355617709991330.

PERTL, M.; BENKE, T.; ZAMARIAN, L.; DELAZER, M. Effects of Healthy Aging and Mild Cognitive Impairment on a Real-Life Decision-Making Task. Journal of Alzheimer's disease : JAD, v. 58, n. 4, p. 1077-1087, 2017. DOI: https://doi.org/ 10.3233/JAD-170119.

DE LEÓN, J. M. R. S. et al. Utilidad clínica y propiedades psicométricas del inventario de síntomas prefrontales (ISP) en el daño cerebral adquirido y las demencias degenerativas. Revista de Neurología, v. 61, n. 9, p. 387, 2015. DOI: https://doi.org/10.33588/rn.6109.2015252.

DE LEÓN, J. M. R. S. et al. Inventario de síntomas prefrontales para la evaluación clínica de las adicciones en la vida diaria: Proceso de creación y propiedades psicométricas. Revista de Neurología, v. 54, n. 11, p. 649,2012. DOI: https://doi.org/10.33588/rn.5411.2012019.

SALTHOUSE, T. Consequences of Age-Related Cognitive Declines. Annual Review of Psychology, v. 63, n. 1, p. 201–226, 2012. DOI: https://doi.org/10.1146/annurev-psych-120710-100328.

SATO, T. et al. Differentiation of Dementia with Lewy Bodies from A lzheimer’s Disease Using the J apanese Version of the Test Your Memory. Journal of the American Geriatrics Society, v. 60, n. 3, p. 594–596, 2012. DOI: https://doi.org/10.1111/j.1532-5415.2011.03852.x.

SWETS, J. A. Measuring the Accuracy of Diagnostic Systems. Science, v. 240, n. 4857, p. 1285–1293, 1988. DOI: https://doi.org/10.1126/science.3287615.

TIERNEY, M. C. et al. The NINCDS-ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer’s disease: A clinicopathologic study of 57 cases. Neurology, v. 38, n. 3, p. 359–359, 1988. DOI: https://doi.org/10.1212/WNL.38.3.359.

TSAI, J. C. et al. Comparing the Sensitivity, Specificity, and Predictive Values of the Montreal Cognitive Assessment and Mini-Mental State Examination When Screening People for Mild Cognitive Impairment and Dementia in Chinese Population. Archives of Psychiatric Nursing, v. 30, n. 4, p. 486–491, 2016. DOI: https://doi.org/10.1016/j.apnu.2016.01.015.

WORLD HEALTH ORGANIZATION. WHO releases report on aging and health [online database]. Rio de Janeiro: WHO, 2015. Disponível em: https://sbgg.org.br/oms-divulga-relatorio-sobre-envelhecimento-e-saude/.

YOKOMIZO, J. E. et al. Cognitive screening test in primary care: Cut points for low education. Revista de Saúde Pública, v. 52, n. 88, 2018. DOI: https://doi.org/10.11606/S1518-8787.2018052000462.

Publicado

2022-10-01

Como Citar

Ferreira, O. D. L. ., Cipriano, J. P. dos S. ., & Alchieri , J. C. (2022). Accuracy of the Brazilian version of the Prefrontal Symptoms Inventory (PSI-16) in the neuropsychological assessment of patients diagnosed with Alzheimer’s disease. Scientific Electronic Archives, 15(10). https://doi.org/10.36560/151020221598

Edição

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Ciências da Saúde