Abstract
Huntington's Disease is a neurodegenerative condition which causes motor losses associated with a great morbidity demential syndrome. Its incidence increases with age. There is no cure, therefore its therapeutical options intend to increase life quality. This case report brings a patient with advanced Huntington`s Disease approached with optimal pharmacological therapy and a transcranial magnetic stimulation protocol, assessed in two different moments on its therapeutical journey, showing improvement on clinical and life quality scores, being necessary more studies to better elucidate the relation between such therapies and the results of this report.
References
- BATES, Gillian P. et al. Huntington disease. Nature reviews Disease primers, v. 1, n. 1, p. 1-21, 2015.
- CARVALHO, Ana Catarina Pereira Quintas Guedes. Doenças neurodegenerativas: uma visão gliocêntrica. 2021.
- CARIMAN, Mariana Oliveira Ramalho; SESTI, Luís Fernando Castagnino. Perfil dos portadores da Doença de Huntington no Brasil. Research, Society and Development, v. 11, n. 7, p. e6511729565-e6511729565, 2022.
- JUNCA, Estefanía et al. Brain, cognitive, and physical disability correlates of decreased quality of life in patients with Huntington’s disease. Quality of Life Research, v. 32, n. 1, p. 171-182, 2023.
- LATORRE, Anna et al. The use of transcranial magnetic stimulation as a treatment for movement disorders: a critical review. Movement Disorders, v. 34, n. 6, p. 769-782, 2019.
- MACHADO, Miriam Caroline Alberti; GONÇALVES, Vanessa Regina. Doença Neurodegenerativa Rara: Uma Análise na Doença de Huntington. 2022.
- MOHAPEL, Joana M. Gil; REGO, Ana Cristina. Doença de Huntington: uma revisão dos aspectos fisiopatológicos. Revista Neurociências, v. 19, n. 4, p. 724-734, 2011.
- NOISEUX, Clémence et al. Repetitive transcranial magnetic stimulation for major depressive disorder comorbid with huntington’s disease: a case report. NeuroSci, v. 2, n. 4, p. 400-404, 2021
- SANTANA, Carlos Fernando Morais; FERREIRA, Lis Campos; MATOS, Marcos Danilo Azevedo. O estado da arte do tratamento da doença de Huntington The state of the art on treatment of Huntington's disease. Brazilian Journal of Health Review, v. 4, n. 3, p. 14016-14033, 2021.
- Zografou , M., & Drigas, A. (2022). The role of executive functions and ICTs in anxiety management of children with learning disabilities. Scientific Electronic Archives, 15(8). https://doi.org/10.36560/15820221573