Marine invertebrates as drug biomarkers
DOI:
https://doi.org/10.36560/14520211278Keywords:
Avaliação ambiental, Ecossistemas aquáticos, Marcadores biológicos, Poluição.Abstract
Ecosystems in general have been experiencing an increasing increase in the process of contamination by pollutants and drugs from agricultural, urban and industrial activities. The measurement of the main contaminants in the environment depends on several factors, where the main concern is with the effects that these substances and medicines can have on the environmental species, mainly the marine invertebrates, in order to harm the ecosystem as a whole. Based on these problems, there are biomarkers that constitute an efficient approach in studies in assessing environmental impacts, identifying real effects that are occurring in living beings exposed to polluted environments. Therefore, the aim of the present study was to analyze data, based on a literature review on marine invertebrates as drug biomarkers. In order to achieve the objective of this work, the methodology used was exploratory research, with the data collection being the bibliographic survey. The choice of the theme is justified because it reflects the importance of the concern with the environment and mainly with the species present in the aquatic environment, due to its vulnerability due to the exposure to various products and substances that can compromise the viability of these organisms. This study sought to assist the population on the importance of concern with marine invertebrates and their exposure to drugs and substances that can cause damage not only to them, but in the entire environment.
References
ALENCAR, T.O.S., et al. Descarte de medicamentos: uma análise da prática no Programa de Saúde da FamÃlia. Ciência & Saúde Coletiva, v. 19, n. 7, p. 2157-2166, 2014.
ARCHER, E., et al. The fate of pharmaceuticals and personal care products (PPCPs), endocrine disrupting contaminants (EDCs), metabolites and illicit drugs in a WWTW and environmental waters, Chemosphere, v. 174, p. 437 – 446, 2017.
ÃVILA, C. et al. Attenuation of emerging organic contaminants in a hybrid constructed wetland system under different hydraulic loading rates and their associated toxicological effects in wastewater, Science of The Total Environment, v. 1, p. 1272-1280, 2014.
BIRCH, G.F., et al. 2015. Emerging contaminants (pharmaceuticals, personal care products, a food additive and pesticides) in waters of Sydney estuary, Austrália. Mar. Pollut. Bull., v 97, pp 56–66, 2015.
BLANCHETTE, B., et al. Marine Glutathione S –Transferases. Marine biotechnology, v. l9, p. 513–542, 2007.
COIMBRA, R. S. C. Biomarcadores como ferramentas na avaliação da qualidade do pescado contaminado com metais traço. Boletim do Observatório Ambiental Alberto Ribeiro Lamego, Campos dos Goytacazes/RJ, v. 7 n. 1, p. 153-172, jan. / jun. 2013.
CUNNINGHAM, V.L., et al. Environmental risk assessment of paroxetine. Environ. Sci. Technol. v. 38, p. 3351-3359, 2004.
CHEN, H., et al. Effects of fluoxetine on behavior, antioxidant enzyme systems, and multixenobiotic resistance in the Asian clam Corbicula fluminea. Chemosphere, v. 119, p 856–862, 2015.
CRUZ, R.M.; et al. Investigação dos medicamentos comercializados nas drogarias e a conduta quanto a polÃtica de descarte. Anais do Congresso de Ensino, Pesquisa e Extensão da UEG, v. 3, 2016.
DAUGHTON, C. G. Pharmaceuticals and the Environment (PiE): Evolution and impact of the published literature revealed by bibliometric analysis. Science of the Total Environment, v. 562, p. 391-426, 2016.
FAWELL, J.; ONG, C. N. Emerging Contaminants and the Implications for Drinking Water. International Journal of Water Resources Development, v. 28, n. 2, p.247-263, 2012.
FENT, K. Ecotoxicological effects at contaminated sites. Toxicology, 205:223-240, 2004.
FERRREIRA, M.S.; et al.2013. Contaminação por metais traços em mexilhões Perna perna da costa brasileira. Ciência Rural: Santa Maria, v.43, n.6, p.1012-1020, 2013.
FILHO et al. Avaliação de biomarcadores histológicos em peixes coletados a montante e a jusante da mancha urbana. Asa, São Paulo, v. 2, n. 1, p. 9-22, Jan/abr. 2014.
GAVRILESCU, M. et al. Emerging pollutants in the environment: present and future challenges in biomonitoring, ecological risks and bioremediation. New Biotechnology, v. 32, n. 1, p. 147–156, 2015
GESTEL, C. A. M.; BRUMMELEN, T. C. Incorporation of the biomarker concept in Ecotoxicology calls for a redefinition of terms. Ecotoxicology, v. 5, n. 4, 217–225pp, 1996.
GOU, J.; et al. Effect of high pressure processing on the quality of squid (Todarodes pacificus) during refrigerated storage. Food Chemistry, v.119, p. 471-476, 2010.
GRACIANI, F.S; FERREIRA, G.L.B.V. Impacto ambiental de los medicamentos y suregulaciónen Brasil. Rev Cubana de Salud Pública: 40(2):268-273, 2014.
IOB, G.A.; et al. Análise da forma de descarte de medicamentos por usuários de uma Unidade de Saúde no municÃpio de Porto Alegre/RS. Rev. Inf. Ciênc. Farm., v. 25, n. 3, p. 118-124, 2013.
JACOBSON, M. Atmospheric pollution. Cambridge University Press, London, 339pp. 2000.
JONES, O. A. H. et al. Potential impact of pharmaceuticals on environmental health, Bulletin of the World Health Organization, v. 81, nº 10, 2003.
KÄFFER, M. I. Biomonitoramento da qualidade do ar com uso de liquens na cidade de Porto Alegre, RS. Tese de Doutorado em Ecologia. Instituto de Biociências. Universidade Federal do Rio Grande do Sul. Porto Alegre. 2011.
KAY, D.; et al.2008. Results of field investigations into the impact of intermittent sewage discharges on the microbiological quality of wild mussels (Mytilus edulis) in a tidal estuary. Water Research, v.41, p.3033- 3046, 2008.
KUMMERER, K. The presence of pharmaceuticals in the environment due to human use – presente knowledge and future challenges. Journal of Environmental Management, 90: 2354-2366, 2009.
LACAZE, E., et al. Linking genotoxic responses in Gammarus fossarum germ cells with reproduction impairment, using the Comet assay. Environ. Res. v. 111, p. 626-634, 2011.
MACHADO, A. A. O local e o global na estrutura da PolÃtica Ambiental Internacional: a construção social do acidente quÃmico ampliado de Bhopal e da convenção da OIT. Contexto Internacional, v. 28, n. 1, p. 8-51, 2006.
MAGALHAES, D. P.; FILHO, A. S. F. A ecotoxicologia como ferramenta no biomonitoramento de ecossistemas aquáticos. Oecol. Bras. v.12, 355-381pp. 2008.
MILAN, M., et al. Gene transcription and biomarker responses in the clam Ruditapes philippinarum after exposure to ibuprofen. Aqua. Toxicol. v. 126, p. 17 - 29, 2013.
MUCELIN, C.A.; BELLINI, M. Lixo e impactos ambientais perceptÃveis no ecossistema urbano: Sociedade & Natureza. Uberlândia. v. 20, n. 1, p. 111 – 124, 2008.
NUNES, B. et al. Biochemical and standard toxic effects of acetaminophen on the macrophyte species Lemna minor and Lemna gibba, Environmental Science and Pollution Research, vol. 21, nº 18, pp. 10815-10822, 2014.
OLIVEIRA, D. P.; KUMMROW, F. Poluentes da Atmosfera. In: OGA, S.; et al. Fundamentos de Toxicologia. 3 ed., São Paulo. Atheneu, 2008.
OLIVEIRA, J.; et al. Microbial contamination and purification of bivalve shellfish: Crucial aspects in monitoring and future perspectives – A minireview. Food Control, v. 22, p. 805-816, 2011.
PACHECO, M.; SANTOS, M.A. Biotransformation, genotoxic, and histophatological effects of environmental contaminants in European eel (Anguilla Anguilla L.). Ecotoxicology and Environmental Safety, v.53, p.331-347, 2002.
PEREIRA, A. R. B; FREITAS, D. A. F. Uso de microorganismos para biorremediação de ambientes impactados. Rev Elet.Gestão, Eduação e Tecnologia Ambiental, v.6, p.975-1006, 2012.
PHAM, Vy.T., et al. On the interaction between fluoxetine and lipid membranes: effect of the lipid composition. Spectrochim. Acta A Mol. Biomol. Spectrosc. 191, 50–61, 2018.
SARKAR, A., et al. Molecular Biomarkers: their significance and application in marine pollution monitoring. Ecotoxicology, 15(4): 333-340, 2006.
SODRÉ, F.F; GRASSI, M.T. Changes in copper speciation and geochemical fate in freshwaters following sewage discharges; Water Air Soil Poll; v. 178; p. 103-112, 2007.
VAZ, K. V.; FREITAS, M. M.; CIRQUEIRA, J. Z. Investigação Sobre a Forma de Descarte de Medicamentos Vencidos, BrasÃlia: Cenarium Pharmacêutico, 2011. DisponÃvel em: < http://www.unieuro.edu.br/sitenovo/downloads/cenarium_04_14.pdf 07/01/2016>. Acesso em: 27 jun. 2020.
WALKER, C., H. et al. Principles of ecotoxicology. 2ª ed. Taylors & Francis. 2004.
ZORITA, I. et al. Assessment of biological effects of environmental pollution along the NW Mediterranean Sea using ed mullets as sentinel organisms. Environmental Pollution, v.153, p. 157-168, 2008.
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